Thyroxine Binding Globulin radioimmunological assay kit RIA

The OCRU3-TBG kit is a radioimmunological assay for TBG to evaluate thyroid function and, combined to the measure of T4, calculate the T4/TBG ratio.
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The OCRU3-TBG kit is a radioimmunological assay for TBG to evaluate thyroid function and, combined to the measure of T4, calculate the T4/TBG ratio.
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In stock

Overview

Assess thyroid function

Use the T4/TBG ratio to differentially diagnose between euthyroidism, hypothyroidism, hyperthyroidism

Diagnose congenital TBG anomalies

Benefits

  • FAST ASSAY
  • ACCURATE AND RELIABLE ASSAY

Assay principle: competition

The serum TBG competes with the 125I-TBG tracer for a limited number of binding sites on highly specific anti-TBG antibodies. Free TBG is separated from the TBG-antibody complex by precipitating the latter with polyethylene glycol (PEG). The 125I-activity in the precipitate is measured.

Assay procedure: 30 min at RT + 20 min centrifugation.

Features

Working range: 0 – 80 µg/mL

Sample: serum or plasma – 20 µL

Normal values for TBG

Age (years) 1 - 10 11 -16 17 - 60 >60
Mean level of TBG (µg/mL) 31,5 24,1 20,5 19,9
Standard deviation 14 6,5 4,8 6,0

TBG in various clinical situations

Clinical situation Euthyroidism goitre Hypothyroidism Hyperthyroidism Oral contraceptives During pregnancy from 10th to 30th w. TBG anomalies
TBG Mean value µg/mL 20,8 ± 4,6 25,3 ± 4,8 19,5 ± 5,0 28,0 ± 5,0 50,0 <10

T4/TBG ratio in various clinical situations

Clinical situation Euthyroidism Hypothyroidism Hyperthyroidism Oral contraceptives
Mean value T4/TBG 4,3 1,1 11,2 3,6
Standard deviation 1,2 0,9 3,6 0,8
Range 3,1 – 5,2 0,2 – 2,0 7,6 – 14,8 2,4 – 4,4

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Annual availability Schedule 2020

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Calendrier de mise a disposition 2020

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Safety Data Sheet (DEU) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ELL) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (FRA-FR) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ITA) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (SPA) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ENG-GB) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ENG-US) TBG / NCRU03-TBG

NCRU03-TBG - Safety Data Sheet

Quality Control Report TBG / NCRU03-TBG

NCRU03-TBG Batch 163A(30mn) - Quality Control Report

Certificat TBG / OCRU03-TBG

OCRU03-TBG - Certificat

Safety Data Sheet (DEU) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ELL) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (SPA) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ENG-GB) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ENG-US) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (FRA-FR) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Safety Data Sheet (ITA) TBG / OCRU03-TBG

OCRU03-TBG - Safety Data Sheet

Quality Control Report TBG / OCRU03-TBG

OCRU03-TBG Batch 163A(30mn) - Quality Control Report

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