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SNAP-Lumi4-Tb labeling reagent HTRF®

SNAP-Tag, Clip-Tag, and HALO-Tag are protein labeling systems enabling the covalent attachement of fluorophores onto proteins of interest. SNAP-Lumi4-Tb enables SNAP-tagged proteins to become labeled with a Terbium fluorophore.
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SNAP-Tag, Clip-Tag, and HALO-Tag are protein labeling systems enabling the covalent attachement of fluorophores onto proteins of interest. SNAP-Lumi4-Tb enables SNAP-tagged proteins to become labeled with a Terbium fluorophore.
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Overview

Over the past few years, SNAP-Tag, CLIP-Tag, and Halo-Tag technologies combined with TR-FRET have paved the road to the development of many non-radioactive, no-wash binding assays. The method is based on transfecting cells using plasmids encoding a SNAP-Tag (or CLIP-Tag, or Halot-Tag) and subsequently labeling them with acceptors or donors. SNAP-Lumi4-Tb allows the labeling of SNAP-Tagged proteins with a terbium fluorophore.

Benefits

  • COVALENT LABELING
  • FAST REACTION

Receptor labeling

SNAP-tag® is a small fusion tag that covalently interacts with specific substrates. SNAP-tag enables the specific and covalent labeling of any protein of interest. Cells are provided unlabeled and need to be labeled with Lumi4-Terbium prior to running a binding assay. Labeling reagents are available from the Cisbio catalog in 4 different sizes. For more details refer to labeling procedure.
Diagram of a chemical reaction between SNAP-tag and its substrate

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Plate Reader Requirement

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