Human IL17 kit
No-wash kit to quantify released Human IL17
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SIRT1 belongs to class III of the silent information regulator 2 (Sir2) family of proteins, which are histone/protein deacetylases (sirtuins). The use of SIRT1 modulators has been described as a potential therapeutic solution for treating multiple disease states including cancer, diabetes, aging, and neurodegenerative, metabolic or cardiovascular diseases. This rapid, simple assay enables the discrimination of polyphenolic compounds and can be used for high throughput screening to identify both inhibitors and activators of SIRT1 activity.
Z' values for different SIRT1 concentrations in twenty-four replicates were run using 4 selected SIRT1 concentrations: 0 mU of enzyme (no deacetylation), 100 mU of enzyme (100% deacetylation), 10 mU and 20 mU corresponding to the EC50 and EC80 respectively.
Titration curves were performed using 3 classes of compounds: two polyphenolic compounds (resveratrol and piceatannol), two non-polyphenolic compounds (activator1 and activator2 and one reference inhibitor (nicotinamide)
Product Insert SIRT Kit / 64SI1PEB
64SI1PEB - Product Insert
Product Insert SIRT Kit / 64SI1PEC
64SI1PEC - Product Insert
HTRF Product Catalog 2020 July update
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
Safety Data Sheet SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (DEU) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (ELL) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (FRA-FR) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (ITA) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (SPA) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (ENG-GB) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet (ENG-US) SIRT Kit / 64SI1PEB
64SI1PEB - Safety Data Sheet
Safety Data Sheet SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (DEU) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (ELL) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (FRA-FR) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (ITA) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (SPA) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (ENG-GB) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
Safety Data Sheet (ENG-US) SIRT Kit / 64SI1PEC
64SI1PEC - Safety Data Sheet
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