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MuSK autoantibody radioimmunoassay kit RIA

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The MSK/TR kit is a radioimmunoassay measuring the muscle-specific receptor kinase autoantibodies (MuSKAb) in human serum in relation to myasthenia gravis.
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The MSK/TR kit is a radioimmunoassay measuring the muscle-specific receptor kinase autoantibodies (MuSKAb) in human serum in relation to myasthenia gravis.
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Overview

Assess patients with acetylcholine receptor antibody (AChRAb)-negative myasthenia gravis

Monitor patients with AChRAb-negative myasthenia gravis

Benefits

  • ACCURATE AND RELIABLE ASSAY

Assay principle:

The sample containing MuSKAb is incubated with 125I-MuSK. Goat antihuman IgG is then added. After a first centrifugation, the precipitates are suspended in a further assay buffer and centrifuged again. Pellets are counted. NB: to carry out MuSKAb measurement, two catalog references are required: MSK/TR kit and RBAN/25 (IPA).

Assay procedure: 1 h RT + 2h at 2-8°C + 20 min centrifugation + 20 min centrifugation.

Features

Working range: negative and positive controls (nmol/L)

Sample: serum – 5 µL

Normal values

MuSKAb values > 0.05 nmol/L bound MuSK are considered as positive.

IVD Product list 2020

Immunoassays RIA and ELISA - Catalog

Catalogue produits IVD 2020

Immuno-analyse RIA et ELISA - Catalog

Annual availability Schedule 2021

In-vitro RIA products - Availability calendar

Calendrier de mise a disposition 2021

Trousse pour radioimmunologie - Availability calendar

Quality Control Report MuSK / MSK--TR

MSK/TR Batch MK201 - Quality Control Report