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Human calcitonin (hCT) immunoradiometric assay kit RIA

The IRMA-HCT assay offers a specific measurement of mature calcitonin to diagnose and monitor medullary thyroid carcinomas (MTC).
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The IRMA-HCT assay offers a specific measurement of mature calcitonin to diagnose and monitor medullary thyroid carcinomas (MTC).
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In stock

Overview

Diagnosis and monitor medullary thyroid carcinomas (MTC)

hCT measurements and pentagastrin test (Pg test) are systematically carried out for an early diagnosis of cancer in at-risk families or in case of relapse among previously operated patients.

Use hCT doubling time as a powerful prognosis factor in MTC-affected patients

Contributes to diagnosis of multiple endocrine neoplasia type II and familial MTC

Can also be used in the diagnosis and monitoring of islet cell tumors

Benefits

  • HIGH SPECIFICITY AND SENSITIVITY
  • WITHOUT CROSS-REACTIVITY WITH PROCT

Assay principle: sandwich

Two monoclonal antibodies, specific to native monomeric calcitonin recognizing the 23 – 32 amide region and the 11 – 17 region respectively, are used for the sandwich. The first antibody is adsorbed onto the tube walls. The second one, radiolabeled with iodine-125, is used as the tracer.

One-step assay procedure: 20-24h at RT.

Features

Working range: 1.5 – 1500 pg/mL (1µIU 2nd IS 89/620 = 3.6 pg CIS)

Sample: serum pretreated by heating 30 min at 56°C – 200 µL

Analytical sensitivity: 1.5 pg/mL

Functional sensitivity: 4.0 pg/mL

Normal values

NB: smokers and past-smokers could exhibit significantly elevated seric hCT
Population
n=98
Reference range
hCT pg/mL
81%<5
96%<10
Population hCT pg/mL
Females <7
Males <12

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Annual availability Schedule 2020

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Product Insert (ENG) HCT / IRMA-HCT

IRMA-HCT Op.Mod.020 - Product Insert

Product Insert (FRA) HCT / IRMA-HCT

IRMA-HCT Op.Mod.020 - Product Insert

Certificat HCT / IRMA-HCT

IRMA-HCT - Certificat

Safety Data Sheet (DEU) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (ELL) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (SPA) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (ENG-GB) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (ENG-US) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (FRA-FR) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Safety Data Sheet (ITA) HCT / IRMA-HCT

IRMA-HCT - Safety Data Sheet

Quality Control Report HCT / IRMA-HCT

IRMA-HCT Batch 477A(20-24h) - Quality Control Report

Quality Control Report HCT / IRMA-HCT

IRMA-HCT Batch 478A(20-24h) - Quality Control Report

Safety Data Sheet (DEU) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (ELL) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (ITA) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (SPA) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (ENG-GB) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (ENG-US) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet

Safety Data Sheet (FRA-FR) HCT / IRMA-HCT-C6

IRMA-HCT-C6 - Safety Data Sheet