Cortisol in human serum and saliva radioimmunoassay kit RIA
Overview
Explore the hypothalamic-pituitary adrenal cortex axis
Use an essential screening tool in hypocortisolism and hypercortisolism
Determine cortisol levels after stimulation and suppression tests
Discriminate between primary and secondary adrenal insufficiency Differentially diagnose Cushing’s syndromes
Benefits
- ACCURATE AND RELIABLE ASSAY
- STANDARDIZED AGAINST MASS SPECTROMETRY
Assay principle: competition
The principle of the assay is based on a competition between iodine-125 radiolabeled cortisol and cortisol contained in the samples for a fixed and limited number of anti-cortisol polyclonal antibody binding sites adsorbed onto the tube walls.
One-step assay procedure: 1- Serum: 2h at 37°C 2- Saliva: 30 min at 37°C
Features
Working range: sérum: 20 – 2000 nmol/L
Working range:salive:1 – 100 nmol/L
Sample: serum: 20 µl;saliva: 150 µL
Analytical sensitivity: sérum: 6.0 nmol/L serum;saliva: 3.0 nmol/L
Normal values
Healthy subjects (20 59 years) | Serum (nmol/L) | Saliva (nmol/L) | ||
---|---|---|---|---|
8 10 am | 3 5 pm | 6 8 am | 6 8 pm | |
n | 220 | 60 | 126 | 124 |
Means (nmol/L) | 308 | 182 | 27.9 | 6.7 |
Reference interval (nmol/L) | 131 - 642 | 61 - 429 | 10.4 - 45.9 | 3.2 - 14.7 |
Confidence intervals 0.90 | ||||
For lower reference limit | 104 - 146 | 6.5 - 12.1 | 2.6 - 3.5 | |
For upper reference limit | 576 - 709 | 45.4 - 52.9 | 12.9 - 16.2 |
Immunoassays RIA and ELISA - Catalog
Immuno-analyse RIA et ELISA - Catalog
Annual availability Schedule 2021
In-vitro RIA products - Availability calendar
Calendrier de mise a disposition 2021
Trousse pour radioimmunologie - Availability calendar
Product Insert (ENG) Cortisol / CORT-CT2
CORT-CT2 Op.Mod.025 - Product Insert
Product Insert (FRA) Cortisol / CORT-CT2
CORT-CT2 Op.Mod.025 - Product Insert
Certificat Cortisol / CORT-CT2
CORT-CT2 - Certificat
Safety Data Sheet (DEU) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (ELL) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (SPA) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (ENG-GB) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (ENG-US) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (FRA-FR) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Safety Data Sheet (ITA) Cortisol / CORT-CT2
CORT-CT2 - Safety Data Sheet
Quality Control Report Cortisol / CORT-CT2
CORT-CT2 Batch 102A(2h) - Quality Control Report
Quality Control Report Cortisol / CORT-CT2
CORT-CT2 Batch 103A(2h) - Quality Control Report
Quality Control Report Cortisol / CORT-CT2
CORT-CT2 Batch 104A(2h) - Quality Control Report
Safety Data Sheet (ENG-GB) Cortisol / KIPI28000
KIPI28000 - Safety Data Sheet