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Cortisol in human serum and saliva radioimmunoassay kit RIA

The CORT-CT2 kit is a radioimmunoassay that measures seric and salivary cortisol levels for the examination of the hypothalamic-pituitary adrenal cortex axis.
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The CORT-CT2 kit is a radioimmunoassay that measures seric and salivary cortisol levels for the examination of the hypothalamic-pituitary adrenal cortex axis.
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In stock

Overview

Explore the hypothalamic-pituitary adrenal cortex axis

Use an essential screening tool in hypocortisolism and hypercortisolism

Determine cortisol levels after stimulation and suppression tests

Discriminate between primary and secondary adrenal insufficiency Differentially diagnose Cushing’s syndromes

Benefits

  • ACCURATE AND RELIABLE ASSAY
  • STANDARDIZED AGAINST MASS SPECTROMETRY

Assay principle: competition

The principle of the assay is based on a competition between iodine-125 radiolabeled cortisol and cortisol contained in the samples for a fixed and limited number of anti-cortisol polyclonal antibody binding sites adsorbed onto the tube walls.

One-step assay procedure: 1- Serum: 2h at 37°C 2- Saliva: 30 min at 37°C

Features

Working range: sérum: 20 – 2000 nmol/L

Working range:salive:1 – 100 nmol/L

Sample: serum: 20 µl;saliva: 150 µL

Analytical sensitivity: sérum: 6.0 nmol/L serum;saliva: 3.0 nmol/L

Normal values

Healthy subjects (20 – 59 years) Serum (nmol/L) Saliva (nmol/L)
8 – 10 am 3 – 5 pm 6 – 8 am 6 – 8 pm
n 220 60 126 124
Means (nmol/L) 308 182 27.9 6.7
Reference interval (nmol/L) 131 - 642 61 - 429 10.4 - 45.9 3.2 - 14.7
Confidence intervals 0.90
For lower reference limit 104 - 146 6.5 - 12.1 2.6 - 3.5
For upper reference limit 576 - 709 45.4 - 52.9 12.9 - 16.2

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Annual availability Schedule 2020

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Product Insert (ENG) Cortisol / CORT-CT2

CORT-CT2 Op.Mod.025 - Product Insert

Product Insert (FRA) Cortisol / CORT-CT2

CORT-CT2 Op.Mod.025 - Product Insert

Certificat Cortisol / CORT-CT2

CORT-CT2 - Certificat

Quality Control Report Cortisol / CORT-CT2

CORT-CT2 Batch 97A(2h) - Quality Control Report

Quality Control Report Cortisol / CORT-CT2

CORT-CT2 Batch 98A(2h) - Quality Control Report