Chromogranin A (CgA) immunoradiometric assay kit RIA

The CGA-RIACT immunoradiometric assay measures CgA thanks to antibodies targeting the core of the molecule (145-245) relatively unaffected by proteolysis.

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The CGA-RIACT immunoradiometric assay measures CgA thanks to antibodies targeting the core of the molecule (145-245) relatively unaffected by proteolysis.

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Overview

Follow guidelines and use as a tool for diagnosis, evaluation of treatment efficiency and prognostic factor for GEP-NETs

Diagnosis and monitor neuroendocrine tumors such as pheochromocytoma, gastrinoma, and carcinoid tumors including Small-Cell lung carcinomas (SCLC)

Use as adverse prognostic factor in prostate cancer independent of PSA

Benefits

HIGH SPECIFICITY AND SENSITIVITY
EASY TO INSTALL AND OPERATE IN LABS

Assay principle: sandwich

Two monoclonal antibodies are used in the sandwich and are directed against the central domain of the molecule (145 - 245), which is less sensitive to proteolysis. The first monoclonal antibody is adsorbed onto the tube walls, while the second one, radiolabeled with iodine-125, is used as the tracer. Assay procedure: 18h at RT + 2h at RT / shaking