Aldosterone radioimmunoassay kit RIA
Overview
Diagnosis primary or secondary hyperaldosteronism in hypertensive patients
Assess different origins of primary hyperaldosteronism
Diagnosis hypoaldosteronism
The Endocrine Society recommends using the aldosterone/renin ratio to detect primary aldosteronism* *Funder JW et al. J Clin Endocrinol Metab. 2008;93(9): 3266-81.
Benefits
- CALIBRATED AGAINST GCMS
- EXTENSIVE DYNAMIC RANGE
Assay principle: competition
The assay is based on a competition between a fixed amount of 125I-aldosterone and the aldosterone contained in the samples for a fixed and limited number of antibody binding sites adsorbed onto the walls of the tube.
NB: prior to urine assay, a specific preparation is required.
One-step assay procedure: 3h at RT / shaking.
Features
Working range: 0 – 1500 pg/mL or 0 – 4150 pmol/L
Sample:
serum or plasma - 200 µL
urine - 500 µL
Analytical sensitivity: 7 pg/mL or 19,4 pmol/L
Normal values
Plasma aldosterone pg/mL | ||||
---|---|---|---|---|
Normal subjects | n | 5th percentile | Median | 95th percentile |
Supine | 25 | 42 | 99 | 201.5 |
Upright | 41 | 97 | 201 | 626 |
Immunoassays RIA and ELISA - Catalog
Immuno-analyse RIA et ELISA - Catalog
Annual availability Schedule 2021
In-vitro RIA products - Availability calendar
Calendrier de mise a disposition 2021
Trousse pour radioimmunologie - Availability calendar
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