AChRAb radioreceptor assay kit RIA

The ACHR-AB kit is a radioreceptor assay for anti-Acetylcholine Receptor autoantibodies (AChRAb) in human serum and plasma in relation to myasthenia gravis.

The ACHR-AB kit is a radioreceptor assay for anti-Acetylcholine Receptor autoantibodies (AChRAb) in human serum and plasma in relation to myasthenia gravis.

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Overview

Contributes to the diagnosis of neuromuscular junction failure in myasthenia gravis

Monitor myasthenia gravis treatment

Benefits

ACCURATE AND RELIABLE ASSAY

Assay principle: sandwich

The receptors radiolabeled with iodine-125 are incubated with test sera and any resulting complexes of labeled receptor and receptor antibody are immunoprecipitated with anti-human immunoglobulin. After centrifugation and washing, the precipitate is counted.

Assay procedure: 2h at RT + 2h or 18-24h at 2-8°C + centrifugation 20 min + centrifugation 20 min à TA.